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KMID : 0854720100300030233
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Korean Journal of Asthma, Allergy and Clinical Immunology
2010 Volume.30 No. 3 p.233 ~ p.236
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Suspicious Eosinophilic Fasciitis Preceding Peripheral T Cell Lymphoma
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Ku Ki-Hwan
Kim Hee-Kyoo
Lee Ho-Sup
Kim Geun-Tae
Oak Chul-Ho
Jung Maan-Hong
Chang Hee-Kyung
Chun Bong-Kwon
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Abstract
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Eosinophilic fasciitis (EF) is characterized by sclerodermalike skin lesions, peripheral eosinophilia and hypergammaglobulinemia. While EF is generally benign course, it may precede hematologic malignancy or Hodgkin’s disease, association with peripheral T-cell lymphoma (PTCL) is extremely rare. A 49-year-old man with edema and induration of both distal extremities. Peripheral blood eosinophil count was 2,530/μL. We suspected EF, however, could not
performed histological diagnosis due to his refusal. After 6 months, he was suffered of abrupt fever, weight loss and
general weakness for 1 months. Erythematous nodular papules of skin and enlarged inguinal lymph nodes were noted.
Biopsies from skin and lymph node showed peripheral T cell lymphoma.
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KEYWORD
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Eosinophilia, Fasciitis, Lymphoma, T cell, Peripheral
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